Maria Constancia O. Carrillo

Maria Constancia O. Carrillo

Professor

Chemistry Unit

Department of Physical Sciences and Mathematics

Biography

PhD in Biochemistry, with research interests in molecular genetics and drug discovery

Interests
  • drug discovery
  • molecular genetics
Education
  • PhD Biochemistry

    University of Illinois at Urbana-Champaign

  • BS Molecular Biology and Biotechnology

    University of the Philippines Diliman

Publications

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(2022). Computer-aided screening for potential inhibitory compounds against a Klebsiella pneumoniae local isolate containing SHV-1 and CTX-M antibiotic resistance genes. Philippine Journal of Health Research and Development.

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(2020). In silico strategies in tuberculosis drug discovery. Molecules.

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(2020). Isolation, identification and antibiogram profiling of bacteria isolated from water, seafood, and macroplastic samples from Baseco Beach, Manila Bay. Philippine Journal of Health Research and Development.

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(2017). Genetic Polymorphisms in NAT1, NAT2, GSTM1, GSTP1 and GSTT1 and Susceptibility to Colorectal Cancer Among Filipinos. Acta Medica Philippina.

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(2017). In silico discovery and in vitro activity of inhibitors against Mycobacterium tuberculosis 7, 8-diaminopelargonic acid synthase (Mtb BioA). Drug design, development and therapy.

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(2016). Synthesis and crystal structure of [2, 7, 12-trimethyl-3, 7, 11, 17-tetraazabicyclo [11.3. 1] heptadeca-1 (17), 13, 15-triene-$ąppa$4N] copper (II) bis (perchlorate). Acta Crystallographica Section E: Crystallographic Communications.

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(2016). Toward antituberculosis drugs: in silico screening of synthetic compounds against Mycobacterium tuberculosis L,D-transpeptidase 2. Drug Design, Development and Therapy.

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(2015). Assessment of bacterial species present in Pasig River and Marikina River soil using 16S rDNA phylogenetic analysis.

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(2015). Generating phenograms using frequent structure mining over metabolic pathways. 2015 6th International Conference on Information, Intelligence, Systems and Applications (IISA).

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(2014). Building phylogenetic trees from frequent subgraph mining techniques on reaction hypergraphs. IISA 2014, The 5th International Conference on Information, Intelligence, Systems and Applications.

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(2014). Virtual screening against M. tuberculosis 7, 8-diaminopelargonic acid synthase (MtbBioA) and in silico toxicity evaluation of top hits. Current Enzyme Inhibition.

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(2013). Virtual screening against Mycobacterium tuberculosis lipoate protein ligase B (MtbLipB) and in silico ADMET evaluation of top hits. Orient. J. Chem.

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(2009). Improved Screening Efficiency for Phenylketonuria using a Modified Bacterial Inhibition Assay Protocol--Autoclaving the Bloodspot. Acta Medica Philippina.

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(2008). Evaluation of ras mutations in Filipino colorectal patients. Acta Medica Philippina.

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