Publications

2016
Galingana, M. O. ; Organo, V. G. A Simple Colorimetric Procedure for Differentiating Anions Using Flower Pigments from Anthurium Andreanum. Oriental Journal of Chemistry 2016, 32, 1347-1352.
Hilvano, E. G. V. ; Yang, G. ; Emnacen, I. A. ; Rybak-Akimova, E. V. ; Billones, J. B. ; Carrillo, M. C. O. ; Noll, B. C. ; Organo, V. G. Synthesis and Crystal Structure of [2,7,12-Trimethyl 3,7,11,17-Tetraazabicyclo[11.3.1]Heptadeca-1(17),13,15-Triene-Κ4N]Copper(Ii)Bis(Perchlorate). Acta Crystallographica E 2016, 72, 1009-1012.
Billones, J. B. ; Carrillo, M. C. O. ; Organo, V. G. ; Macalino, S. J. Y. ; Emnacen, I. A. ; Sy, J. B. A. ; Clavio, N. A. B. ; Concepcion, G. P. Toward Antituberculosis Drugs: In Silico Screening of Synthetic Compounds Against Mycobacterium Tuberculosis L,d-Transpeptidase 2. Drug Design, Development and Therapy 2016, 10, 1147-1157.
2015
Duro, M. V. V. ; Organo, V. G. ; Villarante, N. R. Facile Green Synthesis of Functionalized Dihydropyrimidines in a Protic Deep Eutectic Solvent. Philippine Journal of Health Research and Development 2015, 19, 31-36.
2014
Billones, J. ; Carrillo, M. C. ; Organo, V. ; Macalino, S. J. ; Emnacen, I. ; Sy, J. B.

Virtual Screening Against M. Tuberculosis 7,8-Diaminopelargonic Acid Synthase (Mtbbioa) and in Silico Toxicity Evaluation of Top Hits

. Current Enzyme Inhibition 2014, 10, 105-112.Abstract
Tuberculosis (TB) remains to be one of the major public health concerns worldwide. The continuing emergence of Mtb strains resistant to known drugs makes the campaign for successful TB control and treatment very difficult to accomplish. It is therefore imperative to search for newer chemical entities that could inhibit the growing number of putative drug targets for the development of more efficient anti-tubercular drugs. One such ideal target is the 7, 8- diaminopelargonic acid aminotransferase enzyme (BioA). This enzyme is mainly involved in the bacterium’s lipid biosynthesis and metabolism machinery, and is considered as a very promising target due to the fact that humans lack this enzyme. In this study, structure-based pharmacophore screening, molecular docking, and ADMET evaluation of compounds obtained from the InterBioScreen Synthetic Compounds (IBS SC) were performed against the MtbBioA enzyme. Five compounds from the library showed more favorable binding energies as compared to the enzyme’s known inhibitor, amiclenomycin (ACM). Moreover, a pyridazinyladamantane 2-carboxylic acid and two sulfone derivatives have indicated good ADMET properties. These compounds are predicted to possess desirable properties of a lead and should be the subject of subsequent structural optimization and experimental bioactivity evaluations.
Bernardo, M. K. O. ; Organo, V. G.

Chlorophyll as a Simple, Inexpensive and Environment-Friendly Colorimetric Indicator for No2 Gas

. Oriental Journal of Chemistry 2014, 30, 445-449.
2013
Billones, J. B. ; Carrillo, M. C. O. ; Organo, V. G. ; Macalino, S. J. Y. ; Emnacen, I. A. ; Sy, J. B. A.

Virtual Screening Against Mycobacterium Tuberculosis Lipoate Protein Ligase B (MtbLipb) and In Silico Admet Evaluation of Top Hits

. Oriental Journal of Chemistry 2013, 29, 1457-1468.
2009
Organo, V. G. ; Ye, W. ; Agarwal, P. K. ; Rybak-Akimova, E. V.

Biotinylation of Aminopyridine-Based Macrocycles and Metallomacrocycles, and Inclusion of Biotinylated Iron(Ii) Complex in Avidin

. Journal of Inclusion Phenomena and Macrocyclic Chemistry 2009, 64, 15-21.
Organo, V. G. ; Filatov, A. S. ; Quartararo, J. S. ; Friedman, Z. M. ; Rybak-Akimova, E. V.

Nickel(Ii) Complexes of Monofunctionalized Pyridine-Azamacrocycles: Synthesis, Structures, Pendant Arm “On-Off” Coordination Equilibria, and Peroxidase-Like Activity

. Inorganic Chemistry 2009, 48, 8456-8468.
2008
Rudkevich, D. M. ; Organo, V. G.

Synthetic Nanotubes from Calixarenes

. In Organic Nanostructures; Atwood, J. L. ; Steed, J. W., Ed.; Organic Nanostructures; Wiley-VCH: Germany, 2008; pp. 97-109.
2007
Organo, V. G. ; Sgarlata, V. ; Firouzbakht, F. ; Rudkevich, D. M.

Long Synthetic Nanotubes from Calix[4]Arenes

. Chemistry - A European Journal 2007, 13, 4014-4023.
Wanigasekara, E. ; Leontiev, A. V. ; Organo, V. G. ; Rudkevich, D. M.

Supramolecular, Calixarene-Based Complexes That Release No Gas

. European Journal of Organic Chemistry 2007, 2254-2256.
Organo, V. G. ; Rudkevich, D. M.

Emerging Host-Guest Chemistry of Synthetic Nanotubes

. Chemical Communications 2007, 3891-3899.
2005
Rudkevich, D. M. ; Kang, Y. ; Leontiev, A. V. ; Organo, V. G. ; Zyryanov, G. V.

Molecular Containers for NoX Gases

. Supramolecular Chemistry 2005, 17, 93-99.
Organo, V. G. ; Leontiev, A. V. ; Sgarlata, V. ; Dias, R. H. V. ; Rudkevich, D. M.

Supramolecular Features of Synthetic Nanotubes

. Angewandte Chemie International Edition 2005, 44, 3043-3047.
Sgarlata, V. ; Organo, V. G. ; Rudkevich, D. M.

A Procedure for Filling Calixarene Nanotubes

. Chemical Communications 2005, 5630-5632.